Campbell House is a historic house in downtown Toronto, Canada. It is the oldest remaining house from the original site of the Town of York and was built by Upper Canada Chief Justice Sir William Campbell and his wife Hannah in 1822. The home was designed for entertaining and comfort, and constructed at a time when the Campbells were socially and economically established and their children had grown to adulthood.

The house is one of the few remaining examples of Georgian architecture left in Toronto and is constructed in a style in vogue during the late Georgian era known as Palladian architecture.

The house was originally located on a plot of land 1.5 kilometres to the east of the intersection of what is now Adelaide St. and Frederick St. After Sir William Campbell's death in 1834, the house was willed to his wife, Lady Campbell for her use. After her death in 1844, the property and the contents of the house were auctioned off and the proceeds were distributed amongst their heirs. For most of the 19th century the house was a private residence and maintained. It continued to house various local notables until 1890. By then the neighbourhood had changed into a commercial and industrial zone. The building eventually came to be used by several businesses after the turn of the 20th century as office space and a factory, including a horseshoe nails company and an elevator company.